Future of Sales and Marketing beyond COVID - hybrid event in Vilnius: physical audience of 800 + 300 virtual. Digital marketing, location marketing. How to create MAGIC in new marketing campaigns. Future of Marketing Keynote Speaker

Chances of 2 people in 70 having same birthday? Managing Risk in Banking and Financial Services. Why the greatest risks are combinations of very unlikely events, which happen far more often than you expect. Keynote speaker on risk management

Compliance is Dead. How to build trust. Reputation of banks and financial services. Compliance Risks. Why 100% compliance with regulations, ESG requirements etc is often not enough to prevent reputational damage

Life's too short to do things you don't believe in! Why passionate belief in the true value of what you are selling or doing is the number one key to success. Secret of all leadership and marketing - keynote for 1100 people in Vilnius October 2021

Why you can't innovate on Zoom or Teams meetings - Innovation is almost impossible unless breathing same air, in same room

Why the key to rapid innovation is team diversity - survey global CEOs. Innovation keynote speaker

Future Manufacturing 5.0. Lessons from personal life for all manufacturers. Manufacturing Keynote

Future of Manufacturing: diagnostics; predictive analytics, little data and cybersecurity. Keynote

Manufacturing 5 0: The truth about robots, robotics and automation. Future of Manufacturing Keynote

Manufacturing 5.0 - why Manufacturing 4.0 not enough. Agility and Innovation: Manufacturing Keynote

Future of Manufacturing 5.0 - hyperconnected, sustainable factories and supply chains + human beings

80% of sales are won or lost in 3 seconds - Future of Marketing Keynote Speaker - Pardavimu formule

Micro-dose chemo for cancer using oncolytic viruses. Cancer therapy - future healthcare

Futurist Keynote Speaker: Posts, Slides, Videos - BioTech and MedTech Keynote Speaker

More: http://www.virttu.com. How oncolytic viruses can target radiotherapy - micro-dose radiation to kill cancer cells. Replication of oncolytic viruses inside tumours. Pre-clinical trials. Phase I, Phase II and Phase III clinical trials on oncolytics. Use of oncolytic viruses to treat advanced malignant melanoma and mestatases -- Amgen research using an oncolytic virus developed from HSV (Herpes Simplex Virus). Oncolytic virus conference 2013. Problems with traditional chemotherapy -- side effects. Why Amgen bought an oncolytic viruse for $500m in cash and $500m to be paid if oncolytic trials are fully successful. Investor interest in oncolytic viruses. Oncolytic virus fund. Lessons from the history of research and development in monoclonal antibodies in cancer treatment. Why targeted cancer therapy -- a so-called "magic bullet" is so needed. How oncolytic viruses have been modified so that they cannot replicate in normal cells, but are still able to divide in a wide variety of human cancer cells. History of oncolytic viruses. Arming oncolytic viruses. Using viruses like Seprehvir (HSV-1716), adapted to carry an additional payload: extra genes which teach infected cancer cells to take up a compound containing radioactive iodine from the blood, delivering a micro-dose of radiation inside individual cancer calls. Or adding a gene which teaches cancer cells how to split a harmless pro-drug into two, inside the cell, releasing a very effective chemotherapy (alkylating agent). Targetting oncolytic viruses -- by adapting the feet of a virus to that they latch onto receptors on the surface of specific human cancer cells such as prostate (prostate antigens / PSA). Oncolytic virotherapy: Results of early Phase III Rheolysin clinical trials -- combined oncolytic virus and cancer chemotherapy. Side effects and safety profile of oncolytic viruses in clinical studies. Oncolytic virus Seprehvir has passed an FDA safety review with approval for systemic administration of oncolytic viruses to children with advanced cancer. How genes work in viruses, and how genetic engineering allows us to cut and paste genes from one species into another. Dr Video made by Patrick Dixon author of The Genetic Revolution, Chairman of Global Change Ltd, an advisor to many large pharma companies and Chairman of Virttu Biologics Ltd which owns the oncolytic virus Seprehvir (HSV-1716) and many other variants. Seprehvir has been shown to be highly effective against a wide range of cancers in pre-clinical studies. Seprehvir has been used in clinical trials with strong evidence of impact and almost negligible side effects - trials in glioblastoma (brain cancer), squamous cell carcinoma of head and neck and melanoma. Seprehvir is now being used in clinical trials for mesothelioma (lung cancer caused by asbestos), with others planned for hepatocellular carcinoma (live cancer) and ovarian cancer. OncoVEX GM-CSF developed by BioVex in phase III for advanced melanoma, could become first approved oncolytic virus in the western world. OncoVEX GM-CSF is also in a phase 3 trial for head and neck cancer. Reolysin (owned by Oncolytics Biotech) is in phase 3 clinical trials for head and neck cancer with early results in colorectal cancer. JX-594 is owned by Jennerex and in clinical trials for hepatocellular carcinoma. JX-594 is a thymidine kinase-deleted Vaccinia virus plus GM-CSF. NTX-010 is in clinical trials for small cell lung cancer and neuroblastoma. CGTG-102 (Ad5/3-D24-GMCSF) is owned by Oncos Therapeutics. GL-ONC1 is owned by Genelux in Phase I clinicla trials. Cavatak is being developed to treat malignant melanoma. Oncorine was approved a few years ago in China for treatment of head and neck cancer - built from H101 virus.

Declaration of interest: after writing this article, the author became Chairman of Virttu Biologics Ltd.  The company was subsequently bought by Sorrento Therapeutics Inc in 2017.

http://www.youtube.com/watch?v=Y3VneIw5dBo


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